Why and when is a testicular biopsy performed in patients with azoospermia?

Dr Nisarg Patel of Nisha IVF Centre explains what azoospermia is and how testicular biopsy assists in resolving male infertility issues.

Overcoming infertility is challenging. Azoospermia is one of the causes of male infertility, and it relates to a condition in which there are no sperm in the ejaculate. Obstructive and non-obstructive azoospermia are the two types of this condition, non- obstructive refers to a problem in sperm production, and obstructive azoospermia implies a probpem in sperm ejaculation.

Dr Nisarg Patel of Nisha IVF Centre, considered amongst the best IVF hospital in Ahmedabad, states, 'We perform a testicular biopsy to diagnose the type of azoospermia conditions and also whether the condition can be resolved through surgical repair.

Also, surgical repair can lead to sperm in the semen and successful fertilization. Further treatment of azoospermia includes genetic testing and counselling.'

Testicular biopsy is a surgical procedure to remove a portion of tissue from the testes and examine it under a microscope.

Testicular biopsies are done for diagnosis as well as treatment. For example, a testicular spermatozoon has led to success in fertilization using ICSI. Also, IVF specialists recommend cryopreservation of the testicular tissue for future use.

Similarly, testicular biopsy in men with azoospermia indicates the type of azoospermia which then determines the next course of treatment.

Dr Nisarg Patel, one of the best IVF doctors in Ahmedabad, further explains the testicular biopsy procedure. The IVF doctor will conduct a Testicular biopsy under local or general anaesthesia as an outpatient procedure, either in a clinic or a hospital. The patient will be anesthetized before the incision is made, which is made through the skin. The testicle is cut open, and a small tissue fragment is extracted. The incision and the cut in the skin are stitched up. The procedure is repeated on the other testicle if necessary.

Obstructive azoospermia indicates damage or blockage in the reproductive tract due to bacteria, trauma, surgical damage or congenital defects. Microsurgery is performed to treat these defects. In addition, antibiotics and/or microsurgery are used to treat infection and trauma.

There are several reasons for non-obstructive azoospermia (NOA), some of which may not be ascertained; the main ones are Klinefelter's syndrome, long-term exposure to toxins, a trauma in the reproductive tract and radiation therapy.

About Nisha IVF, Ahemdabad

Nisha IVF is managed by a team of expert fertility doctors who are well acquainted with the latest technology and techniques and strive to offer the best infertility treatments. They focus on minimizing risk and safe treatment procedures to ensure a healthy mother and child while the childbearing experience is seamless and blissful. Nisha IVF has successfully treated 450+ couples, including patients from other parts of Gujarat, India, and globally.

The Nisha IVF Centre is well equipped with state-of-the-art operation theatres, IVF stations, rooms, and specially designed reception and waiting lounge areas. We follow strict hygiene and sanitation protocols, including COVID –safety norms.

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