A 56-year-old man who suffered from chronic back pain for over 30 years due to Ankylosing Spondylitis (AS) has found relief after a successful treatment at a Mumbai hospital. Diagnosed with the condition at the age of 35, the patient experienced severe back pain that he managed with steroids, leading to harmful side effects like weight gain and osteopenia. After years of self-medication and loss of hope, the patient sought medical help. The patient marked an improvement in his condition within just three months, following a long dependency on steroids and painkillers. Dr. Dipti Patel, Consultant Rheumatologist at Wockhardt Hospital, said, “This case highlights the importance of early diagnosis and the effectiveness of biologic medications in treating Ankylosing Spondylitis. Within just three months of starting the treatment, we saw a remarkable reduction in pain and stiffness. Today, the patient leads an active, pain-free life and no longer relies on steroids.” The patient’s treatment plan included gradual weaning off steroids, replacing them with biologic medications. This not only managed his AS but also reversed many of the steroid-induced side effects. What is Ankylosing Spondylitis? According to the World Health Organization (WHO), Ankylosing spondylitis is a chronic inflammatory disease that typically begins in early adulthood and affects the axial skeleton, particularly the sacroiliac joints and spine. While specific causes for AS are unknown, genetic factors seem to play a role. Some common symptoms of AS according to WHO are pain in the back or neck, stiffness in the lower back and hips, and fatigue. AS can be managed and with the right care, patients can live a completely normal life. Disclaimer: This is for informational purposes only and does not replace professional medical advice. Consult a qualified expert for personalized guidance. Also Read: Arjun Kapoor reveals suffering from Hashimoto’s disease: What is it?
12 November,2024 12:51 PM IST | Mumbai | mid-day online correspondentWinter may be approaching, but Mumbai is still waiting to feel its chill. In a city where weather can be unpredictable, the seasonal transition calls for a renewed focus on health and immunity. This time of the year, superfoods become especially valuable, offering a natural support to keep one energised and protected from seasonal ailments. As Mumbai's weather shifts, building resilience against temperature fluctuations is key. From boosting immunity to maintaining steady energy, superfoods tailored to different age groups and health needs can help manage this shift. During the current season, when it starts to get cooler, some superfoods offer exceptional benefits. Jinal Patel, Dietician, Zynova Shalby Hospital, suggests, "Trying foods like spinach, pumpkin, sweet potatoes, and apples can be helpful.” These ingredients, particularly when made into warm soups, provide immune-boosting nutrients and help maintain energy in colder weather. Not only are these deliciously comforting, but they also contribute to a nutrient-rich diet, enhancing overall well-being. Immunity-boosting superfoods to prevent seasonal illnesses The transition between warm and cold weather can lead to an uptick in seasonal illnesses like cold, fever and flu. Patel says superfoods like oranges, lemons, garlic and ginger are especially beneficial for supporting immunity. "These foods are packed with essential nutrients like antioxidants and vitamin C that can help strengthen your immune system," she explains. Incorporating these ingredients into meals or drinks, such as teas and juices, can effectively help guard against infections. Superfoods for children Children, especially those between the age group of 5 to 12 have unique nutritional needs that can be met with the right superfoods. Patel recommends foods like blueberries, strawberries, yogurt and oats as excellent choices, which are ideal for breakfast. These superfoods help keep kids full and energised throughout the day, supporting their healthy growth and development, she notes. Berries and yogurt can be incorporated into smoothies or breakfast bowls for a nutritious and appealing start to the day. Superfoods for elderly individuals Elderly people, too, benefit from age-specific superfoods, especially for maintaining energy and bone health. Patel points out that "foods like nuts, seeds, and leafy greens are enriched with the goodness of omega-3 fatty acids and calcium," which are essential for joint support and bone strength during old age. These nutrient-rich foods help alleviate common issues in older age, such as stiffness and fatigue, particularly in colder months. Managing diabetes with superfoods For individuals managing diabetes, choosing the right foods can be a balancing act between blood sugar control and adequate nutrition. Superfoods such as legumes, lentils, green leafy vegetables and nuts are "low on the glycemic index", which helps in stabilising blood sugar, explains Patel. These foods provide fibre and other nutrients that help maintain steady blood sugar while keeping energy levels up. Incorporating these into regular meals can offer both health benefits and flavour variety. Hydration-friendly superfoods Staying hydrated is crucial even in cooler weather, and superfoods can aid in maintaining optimal hydration. Patel suggests watermelon, cucumber and coconut water as excellent choices. “These options have high water content and support electrolyte balance, keeping you hydrated without the bloated feeling,” she explains. Adding these superfoods to snacks or drinks throughout the day can ensure adequate hydration without compromising on taste. Superfoods for digestive and gut health Sometimes, cooler weather can make it harder to digest heavier meals, but certain superfoods ease digestion and support gut health. "Superfoods like gingers, papaya, kefir and fermented foods can help resolve all your concerns related to your gut health," says Patel. These foods can be particularly helpful after consuming rich, heavier dishes. Fermented foods like kimchi, yogurt or kombucha also introduce beneficial bacteria, which promote a healthy gut. “They have probiotics and enzymes that can not only support your gut health but also make it easier to digest, especially after eating heavier meals,” explains Patel. Nutrient-packed foods for expecting and nursing mothers Pregnant and nursing mothers have increased nutritional demands that can be supported with superfoods. Patel advises having green leafy vegetables, fruits, whole grains, nuts and seeds. These are loaded with essential nutrients beneficial for both mother and baby, she says. Whole foods like these provide vitamins and minerals that support development, making them ideal for women in these life stages. Skin health and hydration during seasonal shifts The fluctuating weather can impact skin health, often causing dryness and irritation. Superfoods rich in antioxidants and healthy fats, like avocados, walnuts, berries, and sweet potatoes, can help maintain skin hydration. Patel says these foods are "jam-packed with healthy fats, antioxidants, and vitamin C", keeping skin moist and hydrated despite weather change. Integrating them into daily meals, such as adding avocados to salads or berries to snacks, can provide skin-friendly nutrients and help manage weather-related dryness. Easy superfood-based meal ideas For easy integration of these superfoods into daily life, Patel recommends the following: Start with smoothies made with a variety of fruits and vegetables like spinach, bananas and berries while blending them with milk, or a dairy alternative. Snacking on mixed nuts or fresh fruits is another simple way to incorporate superfoods. These practical ideas make it easy to add nutrient-dense foods to everyday meals, whether for a busy morning or a quick afternoon snack. To help bring these nutritional powerhouses to your table, mid-day.com has gathered some simple and delicious recipes from chefs that highlight these superfoods, offering a practical way to boost your immunity, energy and overall well-being as the season transitions. Superfood recipes you can try at home Berry detox smoothie This recipe by chef Vinamr Manocha from Vivanta Goa is easy to prepare and can be had at any time of the day. Manocha says, “This could be very well enjoyed by guests who have dietary restrictions of sugar. Being high in protein, it works well with people who are very health conscious.”Ingredients:• Blueberries – 50 gms• Banana – 1• Chopped dates – 5• Greek yogurt – 200 gms• Honey to taste Method:Add all the above ingredients in the blender and blend till no lumps remain. Serve chilled. Serving tip:Add ice while blending to ensure a smoother and lighter mix, approximately 3 cubes. Buddha Bowl This vibrant Buddha Bowl by Lata Chetty from Craycraft, is a wholesome and flavourful medley of fresh, nourishing ingredients. It features creamy Tzatziki and smooth Hummus, paired with the earthy crunch of Red Quinoa for a protein-packed base. Chetty says, “This Buddha Bowl is a little love in a bowl — a perfect mix of vibrant, fresh flavours that come together to nourish you from the inside out. It’s simple, satisfying, and made to bring a smile with every bite.”Ingredients:• Red quinoa – 1/2 cup• Tzatziki (store-bought or homemade) – 1/4 cup• Hummus (store-bought or homemade) – 1/4 cup• Greek yogurt – 1/4 cup• Rocket lettuce – 1 handful• Olive oil – 1 tbsp• Salt and pepper to taste• Optional toppings: Chopped cucumber, cherry tomatoes, avocado slices or roasted chickpeas Method:1. Cook quinoa: Rinse 1/2 cup quinoa, then simmer with 1 cup water for 12-15 minutes until tender.2. Prepare dips: Stir store-bought or homemade tzatziki and hummus.3. Assemble bowl: Layer cooked quinoa at the base of a bowl.4. Add dips: Spoon tzatziki and hummus on top of the quinoa.5. Top with yogurt: Add a few teaspoons of Greek yogurt for extra creaminess.6. Add greens: Scatter rocket lettuce over the top.7. Season: Drizzle with olive oil, and season with salt and pepper.8. Optional toppings: Add any extras like cucumber, tomatoes, or avocado. Acai Bowl This recipe contains various superfoods that blend perfectly into a vibrant dish. "The Acai Bowl, with its beautiful light pink hue and a delightful mix of superfoods, is a perfect balance of health and indulgence. It's a visual treat and a delicious way to energise your day," says Chef Rupesh Ramnath Mokal, Tattva Bar & Café.Ingredients:• Epigamia Greek yogurt – 200 gms• Acai powder – 1/2 tsp• Honey – 2 tbsp (for mixing)• Maple syrup – 1 tbsp• Mixed berries – 100 gms (for garnishing)• Mixed nuts – handful, chopped (for garnishing)• Honey drizzle for finishing Method:1. Mix: In a bowl, add Epigamia Greek yogurt, 1/2 teaspoon of acai powder, honey and maple syrup. Whisk the mixture well until it turns a light pink colour and is smooth.2. Serve: Spoon the light pink acai yogurt mixture into a serving bowl.3. Garnish: Top with mixed berries and chopped nuts. Finish with a drizzle of honey for added sweetness and an appealing look.4. Enjoy: Serve immediately to enjoy the fresh and vibrant flavours. Serving tip:1. If you prefer a deeper colour, you can increase the acai powder slightly, but the light pink hue is visually appealing and ensures a balanced flavour.2. Feel free to add granola or chia seeds for extra crunch and nutrition. Incorporating superfoods into your daily meals doesn’t require drastic changes; simple adjustments can provide significant health benefits. By choosing seasonal superfoods and tailoring them to age and health needs, you can enjoy both the nutritional boost and the satisfaction of flavourful, natural foods.
12 November,2024 10:36 AM IST | Mumbai | Jyoti ShuklaPeople with chronic kidney disease (CKD), Type 2 diabetes, or both were predicted to have elevated cardiovascular disease (CVD) risk from eight to 28 years sooner than someone without those conditions, according to a preliminary study on Monday. Scientists from Northwestern University in Chicago conducted a simulation study to estimate the impact of cardiovascular-kidney-metabolic (CKM) syndrome on cardiovascular disease (CVD) risk prediction. They found that people with CKD alone would have high heart risk eight years earlier than those without the disease. Among diabetics, the risk can hit about a decade sooner than those without it. Among people with both diabetes and CKD, women were predicted to reach elevated risk for CVD 26 years earlier and men 28 years earlier than those with neither condition. “Our findings help to interpret the combination of risk factors that will lead to a high predicted CVD risk and at what age they have an impact on risk,” said lead study author Vaishnavi Krishnan, a researcher at Northwestern University. “For example, if someone has borderline-elevated levels of blood pressure, glucose, and/or impaired kidney function, but they don’t yet have hypertension or diabetes or chronic kidney disease, their risk may not be recognised. Understanding how age interacts with risk factor levels is important to optimise CKM health.” The study found that without CKM syndrome, the expected age to reach elevated CVD risk was 68 years for women and 63 for men. However, with CKM components added to the simulated patient profile, the same risk level was predicted to occur at a much younger age. The findings will be presented at the American Heart Association’s Scientific Sessions 2024 to be held from November 16-18 in Chicago. Also Read: Arjun Kapoor reveals suffering from Hashimoto’s disease: What is it? This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever
11 November,2024 09:21 PM IST | Mumbai | IANSIn a recent interview, Arjun Kapoor opened up about his health issues, revealing that he is suffering from an autoimmune disorder called Hashimoto’s disease, which has led to weight concerns for the actor. “I have something called Hashimoto’s Thyroiditis. Your antibodies fight against you. It’s almost like I can take a flight and gain weight because the body goes into stress,” he told The Hollywood Reporter. The actor also revealed that the condition runs in his family. What is this autoimmune disorder? How does it affect the body? What are its symptoms? Let’s find out. Hashimoto’s disease and its impact on the body Hashimoto’s disease is a common yet often overlooked condition that can impact a person’s quality of life if left untreated. Explaining the condition, Dr. Sonali Shivaji Kagne, Consultant - Endocrinology, Sir HN Reliance Foundation Hospital, Mumbai, says, “Hashimoto’s disease, also known as Hashimoto’s thyroiditis, is a chronic autoimmune disorder where the body's immune system mistakenly attacks the thyroid gland.” She further informs, “The thyroid is a small, butterfly-shaped gland located in the neck, and it plays a crucial role in regulating metabolism, energy levels and overall hormonal balance. In Hashimoto’s disease, the immune attack gradually damages the thyroid tissue, leading to reduced production of thyroid hormones, a condition known as hypothyroidism. Over time, this autoimmune response can cause the thyroid to become inflamed and enlarged, a condition referred to as goiter.” Symptoms to look out for “Hashimoto's disease often develops slowly, and the symptoms can be subtle initially, making it challenging to diagnose early,” says Dr. Kagne. However, some common symptoms include: Fatigue and weakness: Persistent tiredness even after adequate rest Weight gain: Unexplained weight gain despite no change in diet or physical activity Cold sensitivity: Increased sensitivity to cold temperatures Dry skin and hair loss: Skin may become dry, and hair may thin or fall out Constipation: Digestive issues are common due to slowed metabolism Depression or mood changes: Low thyroid hormone levels can impact mood and mental health Irregular menstrual cycles: Women may experience heavier or irregular periods Muscle and joint pain: Aching muscles or stiffness, often unexplained Risk factors for Hashimoto’s disease While this autoimmune condition is often genetic, several factors may increase the likelihood of developing Hashimoto’s disease. Dr. Kagne informs, “Genetic factors contribute to 70 per cent of the risk of development of Hashimoto’s disease, whereas environmental factors probably precipitate the disease in genetically susceptible individuals, contributing to 30 per cent of the risk.” Some risk factors are: Gender and age: Women are at least five to eight times more likely than men to develop Hashimoto’s disease, especially during middle age. Family history: If you have a family member with thyroid disease or other autoimmune disorders (for example, rheumatoid arthritis, type 1 diabetes), your risk may be higher. Existing autoimmune conditions: People with autoimmune diseases such as celiac disease or lupus are at an increased risk of developing Hashimoto’s thyroiditis. High iodine intake: Excessive iodine consumption may trigger thyroid inflammation in susceptible individuals. Radiation exposure: Past exposure to radiation, whether from medical treatments or environmental factors, can increase the risk of thyroid disorders. Also Read: Consuming too much salt? It's harming your health, say experts Is Hashimoto’s disease Treatable? While there is no cure for Hashimoto’s disease, it is highly treatable, and the symptoms can be effectively managed. “With appropriate treatment, patients can lead normal, healthy lives. However, lifelong medication and follow-up with an endocrinologist are usually necessary, as Hashimoto’s disease is a chronic condition,” notes Dr. Kagne. Living with Hashimoto’s disease While medication is essential for treating Hashimoto’s disease, its management goes beyond that. According to Dr. Kagne, a holistic approach can help minimise symptoms and improve overall well-being. Balanced diet: Eating a well-rounded diet rich in fruits, vegetables, whole grains and lean proteins can support overall health. Regular exercise: Engaging in regular physical activity helps combat fatigue, manage weight and boost mood. Aim for a mix of cardio, strength training and flexibility exercises. Stress management: Chronic stress can exacerbate autoimmune conditions. Practices like yoga, meditation or mindfulness can help reduce stress levels. Routine check-ups: Regular follow-ups with your endocrinologist are crucial to monitor thyroid function and adjust medication as needed. Disclaimer: This is for informational purposes only and does not replace professional medical advice. Consult a qualified expert for personalised guidance.
11 November,2024 10:55 AM IST | Mumbai | mid-day online correspondent
Trigger Warning: Mentions of illness and mental health challenges When Manav’s* mother got diagnosed with cancer in early 1990s, it came as a shock for the entire family. “It was shocking. It wasn’t even the last thing we were expecting. When we got the news, we just didn’t know what to do,” he shares, adding, “In those times, the awareness about cancer was limited and we felt helpless. We went to several doctors before we could get the right treatment for her. To see my mom go through all the effects was heartbreaking." National Cancer Awareness Day is observed in India on November 7 to raise awareness about the disease and its treatment. While the resources and support for cancer patients have been increasing over the years, the role of family caregivers in the journey of cancer treatment and recovery is often overlooked, and the support they need is often neglected. Caring for a family member or friend with cancer comes with a lot of responsibility and can be challenging. Dr. Indoo Ammbulkar, Director- Medical Oncology, HCG Cancer Center, Borivali, states, “As a caregiver, you provide physical and emotional support, playing a very significant role in their journey.” Besides extending physical and logistical support like helping them with day-to-day activities, taking them for treatment sessions, etc., caregivers also have to play other roles. Dr. Ammbulkar suggests the following ways family and friends can support patients: Get the facts right It is important to be informed about the type of cancer, various treatment alternatives, and the chances of success. With that information, you will help your loved one through the stage and prepare for potential side effects. Consult with your oncologist to better understand the treatment process and what other resources might be helpful for you and the patient. Motivate them Cancer treatment is very exhaustive, not just physically but mentally as well. Be a source of inspiration for them by spending time with the patient to improve their mood. Just sitting there for each session of treatment, talking about their improvement, or listening to them has a huge impact. Plan for financial concerns Arrange finances. This is usually a major concern. Meet with the oncologist and a financial advisor to understand the cost of treatment and any insurance or financial aid options. Some organisations offer support for cancer patients and families. Early planning can ease financial pressures, allowing you to focus on caregiving. Support the mental well-being of the patient Not only does cancer affect the patient but also the emotional well-being of the care partner. Positivity is key for best results; provide encouragement and comfort, where the patient knows they're not alone in this journey and heard. Alongside that, the caregiver should also ensure their well-being. While family and friends often fulfill the responsibility of the caregiver, one often forgets that they might also need motivation and encouragement and they might also need support for their mental well-being. Challenges faced by family caregivers of cancer patients To see a loved one go through the complications of cancer can cause emotional turmoil. Manav shares, “My mom had a traditional mindset and we had to struggle to get her to take medicines or go for treatment. I saw my father dedicate so much time to her well-being, from taking her to doctors to caring for her at home both during and after the treatment.” Dr. Shubhangni Jain, a Delhi-based counselling and rehabilitation psychologist and educator, who has also been a caregiver for a cancer patient in her family, shares, “Knowing that a loved one has been diagnosed with cancer is a shocking and deeply emotional experience. Initially, it was a mix of disbelief and numbness, with emotions that range from intense sadness to anger and fear.” The impact of a cancer diagnosis can affect the well-being of family caregivers in several ways. Utkarsha Jagga, a Delhi-based counselling psychologist and founder of The Coping Central, notes, “Family and friends of cancer patients often experience anxiety, fear, sadness and a sense of helplessness. The caregivers can struggle with the uncertainty that comes along with the diagnosis and might also develop a sense of hypervigilance toward their health and other people’s health. The strain of caregiving can lead to burnout, especially when balancing other responsibilities, and may also trigger feelings of isolation or grief as they witness their loved one’s struggle.” Dr. Jain elaborates on the various challenges that a caregiver might face and must be prepared for: Emotional and psychological distress: Family members and close friends often experience a range of intense emotions, including fear, sadness, guilt, anger and helplessness. They can experience anxiety, depression and other mental health issues. Physical impact: Caregivers often experience physical strain due to increased responsibilities and disrupted routines, such as sleepless nights or managing medications. Financial and logistical challenges: Cancer treatment can be financially draining. Loved ones might face pressure to manage or contribute to high treatment costs, potentially disrupting their work and affecting financial stability. Social isolation: Family members often have limited time for social interactions, as caregiving takes precedence. This can lead to a sense of isolation, as they may feel misunderstood by those who haven’t experienced similar circumstances. Also Read: Look beyond lumps for breast cancer symptoms, urge doctors How did she deal with these challenges in her journey as a caregiver? “Acknowledging these feelings without judgment helped me to create space for genuine processing. We, within our family, sat together and discussed the situation and how to move forward with this shocking news. We had a detailed discussion with doctors and tried to understand even the small details about the problem and treatment. All of us divided our roles rather than leaving everything to one person. This somehow strengthened our family bond as well. We focused on each day, each symptom and each side effect of surgery, chemotherapy and radiation therapy of our loved one. We tried our best to keep ourselves calm and positive,” Dr. Jain says. How can caregivers support their well-being? Given the range of experiences that a caregiver undergoes alongside the patient, it becomes important for them to care for their well-being as much as they care for their loved one’s health. Cancer and mental health experts share tips to ensure that. Dr. Ammbulkar suggests, “Caregiving is an exhausting role that can quickly lead to burnout. Self-care must be incorporated. Time for one's self, pursuing hobbies and attending support groups for caregivers is highly recommended for shared experiences and strategies on the situation. Your well-being will make you a much stronger support for your loved one,” adding, “Most hospitals have cancer support groups for various communities. Caregivers can find solace in these networks, gaining insights and camaraderie from others who have had similar experiences. Seek out these resources with the advice of your oncologist pr psycho-oncologist.” Jagga says, “A cancer diagnosis and caretaking for a loved one with that diagnosis can be a life-changing experience. Along with the patient, the caregiver should be advised to have a strong support system and a consistent channel of reliable information and knowledge. It is often advisable for caregivers to undergo personal therapy as discussing feelings and concerns can reduce stress. It is also helpful to learn to establish realistic caregiving limits and ask for help from others.” “Missing your old life, and the connection that you might have had with the patient is very common, but developing new routines and being able to connect with the patient (and others in their lives) in a new way is extremely important to ensure well-being. Caregiving can be physically demanding, so caregivers should aim to maintain their health through proper nutrition, exercise and rest,” she adds. From her personal and professional experience, Dr. Jain shares the following tips for caregivers: Prioritise communication: Open, honest communication with the patient, medical team and other family members is essential. Regularly check in with the patient to understand their needs and emotions. Build a support network: Caregivers don’t have to face the journey alone. Enlist the help of family, friends or community resources to share responsibilities. Stay informed: Understanding the patient’s diagnosis, treatment options and potential side effects can empower you to make informed decisions and reduce anxiety. The more you know, the better equipped you’ll be to support the patient effectively. Practice self-care and set boundaries: Caregivers often overlook their health and well-being, but self-care is essential. Ensure you’re eating well, staying active and getting enough sleep. Set boundaries around what you can realistically handle. Seek professional counselling if needed: Counselling can offer a safe space to process complex emotions, reduce stress and build coping strategies. Many cancer centres provide resources and referrals for caregiver support. Celebrate small wins: Cancer journeys are emotionally demanding, so take time to celebrate small milestones or good days. These moments can offer motivation and uplift your spirits. Remember your “why”: Reflect on why you’re in this role and the love and connection that motivates you. Recognising your deeper purpose as a caregiver can provide resilience on tough days and a sense of fulfillment despite hardships. Embrace flexibility and patience: Cancer journeys rarely follow a straightforward path. Be flexible in adjusting to unexpected changes and approach the experience with patience. Focus on one day at a time: The cancer journey can be unpredictable, with many highs and lows. Try not to dwell too much on the future; focus instead on managing each day as it comes. *Name changed Disclaimer: This is for informational purposes only and does not replace professional medical advice. Consult a qualified medical expert for personalised guidance.
10 November,2024 10:07 PM IST | Mumbai | Raaina JainA team of US researchers has developed a new genetic model for breast cancer that could help scientists better understand why and where cancer metastasises. Professor Eran Andrechek from Michigan State University in the US has been researching the E2F5 gene and its role in the development of breast cancer. Based on findings from Andrechek’s lab, the loss of E2F5 results in altered regulation of Cyclin D1, a protein linked to metastatic breast tumours after long latency. The study, published in the journal Oncogene, also demonstrated that the removal of E2F5 in the mammary gland leads to tumour formation. As scientists better understand how genes impact breast cancer, they could also learn why cancers metastasize and where cancers are likely to spread. According to Andrechek, while a genetically engineered mouse model can be artificially tweaked through injection to force cancer cells to go to organs like the liver or brain, his lab’s newly generated mouse model makes that unnecessary. “One of the reasons that we’re really excited about this model is that it does something that most genetically engineered mouse models have not done in the past,” Andrechek said. According to Andrechek, breast cancer most often spreads to the lymph nodes, bones or liver. Andrechek’s lab uses bioinformatics (using computer technology to capture and interpret biological data) along with genetic models to examine the mechanisms involved in the development and progression of breast cancer. Its research focuses on understanding mammary tumour development and uses several methods ranging from animal models to computational analysis of gene expression data. While breast cancer can happen at any age, most women are in their 60s or 70s when they are first diagnosed with the disease. Andrechek’s research is physiologically relevant since it takes about two years for the mice to develop a tumour, which means the mice are getting breast cancer at an equivalent age as women. This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever
10 November,2024 05:23 PM IST | New York | IANSIn a first, a team of scientists has introduced a flagship AI dataset from a study of biomarkers and environmental factors that might influence the development of type 2 diabetes. Since the study participants include people with no diabetes and others with various stages of the condition, the early findings hint at a tapestry of information distinct from previous research, according to the report published in the journal Nature Metabolism. “We see data supporting heterogeneity among type 2 diabetes patients — that people aren’t all dealing with the same thing. And because we’re getting such large, granular datasets, researchers will be able to explore this deeply,” said Dr Cecilia Lee, a professor of ophthalmology at the University of Washington School of Medicine in the US. For example, data from a customised environmental sensor in participants’ homes show a clear association between disease state and exposure to tiny particulates of pollution. The collected data also include survey responses, depression scales, eye-imaging scans and traditional measures of glucose and other biologic variables. “All of these data are intended to be mined by artificial intelligence for novel insights about risks, preventive measures, and pathways between disease and health,” the authors noted. The aim is to gather health information from a more racially and ethnically diverse population than has been measured previously, and to make the resulting data ready, technically and ethically, for AI mining. “This process of discovery has been invigorating. We’re a consortium of seven institutions and multidisciplinary teams that had not worked together before. But we have shared goals of drawing on unbiased data and protecting the security of that data as we make it accessible to colleagues everywhere,” said Dr Aaron Lee, also a UW Medicine professor of ophthalmology and the project’s principal investigator. Hosted on a custom online platform, the data are produced in two sets: a controlled-access set requiring a usage agreement, and a registered, publicly available version stripped of HIPAA-protected information. This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever
10 November,2024 05:12 PM IST | New York | IANSAmid a report on high lead levels found in turmeric sold in Asia, including India, doctors on Saturday warned that lead exposure through contaminated turmeric can impair kids’ cognitive functions, and raise heart disease, and stroke risk in adults. The study, published in the journal Science of The Total Environment, found that turmeric sold in India’s Patna; Pakistan’s Karachi and Peshawar; and Nepal had lead levels in turmeric exceeding 1,000 micrograms/gram. This is about 200 times more than the limit set by the Food Safety and Standards Authority of India (FSSAI) -- 10 micrograms/gram. Researchers led by the University of Stanford in the US, along with those from India, found that turmeric sold in Guwahati and Chennai also exceeded the regulatory limit. “Turmeric, widely recognised for its anti-inflammatory and antioxidant properties, is often consumed in significant quantities, making lead contamination especially dangerous. Lead exposure through contaminated turmeric can cause gastrointestinal toxicity, manifesting as abdominal pain, nausea, vomiting, and constipation,” Dr. Mahesh Gupta, Senior Consultant - Medical Gastroenterology, Dharamshila Narayana Hospital, told IANS. “This study serves as a reminder to approach traditional remedies with caution, as overdose or consumption of contaminated turmeric could worsen health rather than improve it,” he added. The study showed that the most likely source of lead in turmeric samples was lead chromate -- a yellow pigment used in paints, rubber, plastics, and ceramic coatings. Polished roots and loose powder were the only forms of turmeric with lead levels above 1,000 micrograms/gram. “Consumption of lead chromate via turmeric has severe health consequences, which include cognitive impairment, especially irreversible damage to a child's brain development. Children can have learning disabilities, including low IQs, and long-term exposure in adults can increase the risk of heart disease and strokes, and can also lead to certain different neurological disorders,” Dr Manisha Arora, Director - Internal Medicine at the CK Birla Hospital (R), Delhi, told IANS. Gupta said regular intake can also impact liver function, impair the organ’s ability to detoxify the body, and lead to oxidative stress in the gastrointestinal lining, which can aggravate inflammatory conditions like gastritis, peptic ulcers, and even irritable bowel syndrome (IBS). Given that loose, unregulated turmeric often exceeds safe lead levels, consumers with digestive sensitivities should be especially cautious, opting for packaged and branded turmeric products that meet regulatory standards, the experts noted. They called on health authorities to focus on eliminating the use of lead chromate in the turmeric supply chain. Raising awareness about the risks associated with contaminated turmeric, coupled with rigorous testing, is essential to safeguarding gastrointestinal health and preventing long-term toxic exposure. Also Read: Consuming too much salt? It's harming your health, say experts This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever
09 November,2024 04:39 PM IST | Mumbai | IANSWhile the brain is commonly known to work for and store memories, a new study showed that other parts of the body can also store memory. The study, which appears in the journal Nature Communications, may pave a new way for treating memory-related afflictions. Nikolay V. Kukushkin, lead author from the New York University in the US stated that “other cells in the body can learn and form memories, too” The researchers found that similar to brain cells, the non-brain cells also turn on a "memory gene" -- in response to new information. Brain cells turn on the "memory gene" -- when they detect a pattern in the information and restructure their connections to form memories. Further, to monitor the memory and learning process in the non-brain cells, the team engineered these to make a glowing protein -- which signalled whether the memory gene was on or off. The experiment revealed that the non-brain cells could determine when the chemical pulses, which imitated bursts of neurotransmitters in the brain, were repeated. The team found that the process is rather similar to the brain when neurons register new learning. It was also found more efficient, just as neurons in our brain can register when we learn with breaks rather than cramming all the material in one sitting. When the pulses were delivered in spaced-out intervals, they turned on the "memory gene" more strongly, and for a longer time, than when the same treatment was delivered all at once, the team said. Kukushkin said the study revealed, “that the ability to learn from spaced repetition isn't unique to brain cells”. It “might be a fundamental property of all cells," the researcher said. Besides offering new ways to study memory, the study also suggests treating “our body more like the brain” for better health. Also Read: ‘Hidden’ form of leprosy can silently affect brain, spinal cord: AIIMS Bhubaneswar study This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever
09 November,2024 12:06 PM IST | Mumbai | IANSNeha Dhupia has shared that with her daughter Mehr she focusses on normalising menstruation and addressing it as a natural part of life. The actress said, as a mother to a girl and son Guriq, she is committed to fostering awareness and education for both of them. “I was fortunate to grow up in a household where open conversations were always welcome. It wasn't a topic we discussed as a family in the living room with my dad and brother around, but I was raised in an educated, modern environment where my mother and I could have these conversations privately,” Neha said at the GoFloRun, which invites women to participate in a run to raise awareness about menstrual hygiene and overall health. She added: “Today, as a mother, to a daughter and son both, I’m committed to fostering awareness and education for both of them.” The actress said that with her daughter Mehr she focusses on “normalising menstruation”. “With my daughter, I focus on normalizing menstruation and addressing it as a natural part of life. This approach is even more important today, given the rising statistics of young girls experiencing early menstruation,” she added. The actress added: “While my journey may not be unique, I recognize how different it is from that of women who don’t have access to this kind of education and support.” - Neha married actor Angad Bedi, the son of former Indian cricket captain Bishan Singh Bedi in a private ceremony at a Gurudwara in 2018. The two welcomed their daughter Mehr Dhupia Bedi in the same year. In July 2021, she and Angad announced that they are expecting their second child with an Instagram post. She gave birth to her second child, a boy in October 2021 and named him Guriq Singh Dhupia Bedi. Also Read: Exclusive | 'It's our responsibility to dismantle this stigma': Tisca Chopra on breaking the taboo around menstruation
08 November,2024 01:37 PM IST | Mumbai | IANSExercising for five minutes per day could reduce blood pressure, a new research has found. The research, which was published by experts from an international academic collaboration led by the University of Sydney and University College London on Thursday, suggested that doing five minutes of physical activity, such as walking uphill or stair climbing every day may help to lower blood pressure. According to the study by the Prospective Physical Activity, Sitting and Sleep (ProPASS) Consortium, replacing sedentary behaviour with 20-27 minutes of exercise per day can result in a clinically meaningful reduction in blood pressure. "High blood pressure is one of the biggest health issues globally, but unlike some major causes of cardiovascular mortality there may be relatively accessible ways to tackle the problem in addition to medication," Emmanuel Stamatakis, joint senior author and director of the ProPASS Consortium from the University of Sydney, said. "The finding that doing as little as five extra minutes of exercise per day could be associated with measurably lower blood pressure readings emphasises how powerful short bouts of higher intensity movement could be for blood pressure management." The research team analysed data from 14,761 volunteers to see how replacing one type of movement with another is associated with blood pressure. The team estimated that replacing sedentary behaviour with at least 20 minutes of exercise daily could reduce cardiovascular disease incidence by 28 per cent. The World Health Organisation estimated that 1.28 billion adults aged 30-79 years worldwide have hypertension, consistent elevated blood pressure, and that 46 per cent of adults with hypertension are unaware they have the condition. Also Read: Physical inactivity on the rise: Experts share ways to incorporate exercise amid sedentary lifestyle and hectic schedules This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever
08 November,2024 12:55 PM IST | Mumbai | IANSADVERTISEMENT
